Monomeric CRP Aggravates Myocardial Injury After Myocardial Infarction by Polarizing the Macrophage to Pro-Inflammatory Phenotype Through JNK Signaling Pathway.

Zhimin ZhaYujia ChengLu CaoYanxia QianXinjian LiuYan GuoJunhong Wang

Published in: Journal of inflammation research (2021)

Taken together, our results imply that mCRP impairs myocardial repair after myocardial infarction by polarizing the macrophages into the pro-inflammatory M1 phenotype via the JNK-dependent pathway.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
cell death
epithelial mesenchymal transition
left ventricular
adipose tissue
endoplasmic reticulum stress
oxidative stress
cell proliferation
atrial fibrillation