Cross-regulation in a three-component cell envelope stress signaling system of Brucella .

Xingru ChenMelene A AlakavuklarAretha Fiebig Sean Crosson

Published in: mBio (2023)

fitness in the presence of cell envelope disruptors and within infected mammalian host cells. Our study reveals a new molecular mechanism of TCS-dependent gene regulation, and thereby advances fundamental understanding of transcriptional regulatory processes in bacteria.

Keyphrases

single cell
cell therapy
induced apoptosis
transcription factor
gene expression
body composition
cell cycle arrest
oxidative stress
cell death
signaling pathway
heat stress