Evaluation of PD-L1 Expression in Colorectal Carcinomas by Comparing Scoring Methods and Their Significance in Relation to Clinicopathologic Parameters.

Mirela FrančinaMislav Mikuš Marin MamićTihomir JovanovićMario ĆorićBožica LovrićIvan VukojaGoran ZukanovićKristijan MatkovićJasmina RajcFerdinand SlišurićMateja Jurić-MareljaGoran Augustin Ilijan Tomas

Published in: Diagnostics (Basel, Switzerland) (2024)

These results suggest that the total number of PD-L1-expressing cells, including tumor and immune cells, is a more sensitive biomarker than the number of PD-L1-expressing tumor cells alone in CRC.

Keyphrases

induced apoptosis
cell cycle arrest
high grade
endoplasmic reticulum stress
cell death
signaling pathway
oxidative stress
pi k akt
wild type