Clinical trial: Combination allopurinol-thiopurine versus standard thiopurine in patients with IBD escalating to immunomodulators (the DECIDER study).

Abhinav Vasudevan Danny Con Peter De Cruz Miles Patrick Sparrow Antony B FriedmanMayur GargSoleiman KashkooliPeter R GibsonDaniel R Van Langenberg

Published in: Alimentary pharmacology & therapeutics (2023)

Thiopurine-allopurinol therapy is safe and mitigates thiopurine adverse effects, thus enhancing tolerability without compromising efficacy (ACTRN12613001347752).

Keyphrases

clinical trial
open label
study protocol
phase ii
radiation therapy
bone marrow
cell therapy
phase iii
smoking cessation
placebo controlled