S-ICD is effective in preventing sudden death in arrhythmogenic cardiomyopathy athletes during exercise.

Here, we describe the cases of two elite athletes, with a diagnosis of arrhythmogenic cardiomyopathy (ACM), in which a subcutaneous implantable cardioverter defibrillator (S-ICD) has been implanted. Both patients experienced a ventricular tachycardia during exercise and received effective S-ICD shocks that interrupted arrhythmias. This report reveals for the first time that the S-ICD is effective in reverting arrhythmias in ACM patients, even during exercise. Moreover, these cases may confirm that competition/physical activity is associated with ICD shocks.