Oxidative stress biomarkers in Fabry disease: is there a room for them?
C SimonciniS TorriV MontanoL ChicoF GruossoA TuttolomondoA PintoI SimonettaV CianciA SalviatiV VicenziG MarchiD GirelliD ConcolinoS SestitoM ZeddeG SicilianoMichelangelo MancusoPublished in: Journal of neurology (2020)
Oxidative stress occurs in FD in both treated and naïve patients, highlighting the need of further research in oxidative stress-targeted therapies. Furthermore, we found that oxidative stress biomarkers may represent early markers of disease in treatment-naïve patients with a potential role in helping interpretation of FD-related mutations and time to treatment decision.