Research on the Mechanism of Liuwei Dihuang Decoction for Osteoporosis Based on Systematic Biological Strategies.

Zhi-Yong LongJia-Min WuWang XiangMeng-Xia YuanYong-He WuJun Li Gan-Peng Yu Tiejun Yang

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

LDD may have a therapeutic effect on osteoporosis through regulating the targets (such as ALB, IGF1, SRC, and ESR1), biological processes (such as positive regulation of calmodulin 1-monooxygenase activity, estrogen metabolism, and endothelial cell proliferation), and pathways (such as JAK-STAT signaling pathway, osteoclast differentiation, and degradation of the extracellular matrix) found in this research.

Keyphrases

extracellular matrix
pi k akt
cell proliferation
postmenopausal women
signaling pathway
bone mineral density
estrogen receptor
tyrosine kinase
endothelial cells
cell cycle
protein kinase
epithelial mesenchymal transition
binding protein
oxidative stress
growth hormone