A new lignan from the flowers of Hibiscus sabdariffa L. (Malvaceae).
Truong Van Nguyen ThienLien Thi My DoPhu Hoang DangNgoc Vinh HuynhHuu Phuc DangThanh Tien NguyenKim Thuy TranDuc Minh Nguyen HuuQuang Ton ThatPublished in: Natural product research (2019)
From MeOH-soluble fraction of the flowers of Hibiscus sabdariffa (Malvaceae), one new lignan, (+)-4-O-methyl-5'-methoxy-secoisolariciresinol (1), together with four known compounds (2-5) were isolated. The structures were elucidated based on NMR spectroscopic analysis. The absolute configuration of 1 was determined based on the Cotton effects in the CD spectrum. Compounds 1, 3 and 4 showed antioxidant activities with the SC50 values of 56.9, 19.3 and 22.7 µM, respectively.