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Interlaboratory concordance of p16/Ki-67 dual-staining interpretation in HPV-positive women in a screening population.

Maria BenevoloPamela MancusoElena AlliaDaniela GustinucciSimonetta BullettiElena CesariniFrancesca Maria CarozziMassimo ConfortiniSimonetta BisanziGabriele CarlinfanteTeresa RubinoFrancesca RolloNatalina MarchiAngelo FarruggioTeresa PusiolFrancesco VenturelliPaolo Giorgi Rossinull null
Published in: Cancer cytopathology (2020)
The p16/Ki-67 assay showed poor reproducibility for adequacy and good reproducibility for positivity comparable to that of cervical cytology. Nevertheless, the low reproducibility does not affect the sensitivity for CIN-2+.
Keyphrases
  • high grade
  • neoadjuvant chemotherapy
  • cervical cancer screening
  • polycystic ovary syndrome
  • high throughput
  • squamous cell carcinoma
  • type diabetes
  • radiation therapy
  • lymph node
  • breast cancer risk
  • locally advanced