A PD-1 /PD-L1 proximity assay as a theranostic marker for PD-1 blockade in patients with metastatic melanoma.
Isabelle GiraultJulien AdamShensi ShenSéverine RoyCaroline BrardSara FaouziEmilie RoutierJeremy LupuSarah WarrenKristina SorgSuFey OngPascale MorelJean Yves ScoazecStéphan VagnerCaroline RobertPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
The proximity between PD-1 and PD-L1, easily assessed by this PLA on one FFPE section, appears as a new biomarker of anti-PD1 efficacy.
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