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Risks of hypertension and thromboembolism in patients receiving bevacizumab with chemotherapy for colorectal cancer: A systematic review and meta-analysis.

Akshit ChitkaraNirmaljot KaurAditya DesaiDevanshi MehtaFnu AnamikaSrawani SarkarNandini GowdaPrabhdeep SethiRajat ThawaniEmerson Y Chen
Published in: Cancer medicine (2023)
BVZ, when added to the standard chemotherapy regimen for mCRC, was associated with higher odds of developing HTN and thromboembolism, specifically ATE, than the chemotherapy-only group. Our findings are significant as they provide vital information in analyzing the risk-benefit ratio of adding BVZ to the standard chemotherapy regime in patients with mCRC, especially in patients with vascular comorbidities.
Keyphrases
  • locally advanced
  • blood pressure
  • squamous cell carcinoma
  • healthcare
  • chemotherapy induced
  • risk assessment