The differential crosstalk of the skin-gut microbiome axis as a new emerging actor in systemic sclerosis.

Edda RussoSilvia Bellando-RandoneDavide CarboniBianca Saveria FiorettoEloisa RomanoSimone BaldiKhadija El AoufyMatteo RamazzottiIrene RosaGemma LepriLeandro Di GloriaMarco PallecchiCosimo BruniDaniela MelchiorreSerena GuiducciMirko ManettiGian Luca BartolucciMarco Matucci-CerinicAmedeo Amedei

Published in: Rheumatology (Oxford, England) (2023)

Different microbiota signatures and FFA profiles were found in the two groups of patients. Despite being in different body districts, the cutaneous Sphingobacteria and faecal Lentisphaerae appear interdependent.

Keyphrases

systemic sclerosis
interstitial lung disease
end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
dna methylation