The individual contributions of blaB, blaGOB and blaCME on MICs of β-lactams in Elizabethkingia anophelis.

Pei-Jing ChenMei-Chen TanWei-Cheng HuangShu-Yuan HsuTe-Li ChenChiou-Ying YangShu-Chen Kuo

Published in: The Journal of antimicrobial chemotherapy (2024)

The constitutionally and highly expressed blaB gene in E. anophelis was responsible for increased MICs of carbapenems and led to their poor in vivo efficacy. blaCME increased the MICs of ceftazidime and cefepime.

Keyphrases

genome wide
gene expression
dna methylation
genome wide identification
transcription factor
multidrug resistant
light emitting