Baicalin improves the functions of granulosa cells and the ovary in aged mice through the mTOR signaling pathway.

Huiying FanJiahuan HeYucheng BaiQina HeTongwei ZhangJunya ZhangGuang YangZiwen XuJingyi HuGuidong Yao

Published in: Journal of ovarian research (2022)

These results indicate that Baicalin could improve the viability of ovarian granulosa cells and the secretion of steroid hormones and thus could help to improve degenerating ovarian function and delay ovarian aging.

Keyphrases

induced apoptosis
signaling pathway
cell cycle arrest
endoplasmic reticulum stress
polycystic ovary syndrome
type diabetes
cell death
metabolic syndrome
adipose tissue
insulin resistance