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Baicalin improves the functions of granulosa cells and the ovary in aged mice through the mTOR signaling pathway.

Huiying FanJiahuan HeYucheng BaiQina HeTongwei ZhangJunya ZhangGuang YangZiwen XuJingyi HuGuidong Yao
Published in: Journal of ovarian research (2022)
These results indicate that Baicalin could improve the viability of ovarian granulosa cells and the secretion of steroid hormones and thus could help to improve degenerating ovarian function and delay ovarian aging.
Keyphrases
  • induced apoptosis
  • signaling pathway
  • cell cycle arrest
  • endoplasmic reticulum stress
  • polycystic ovary syndrome
  • type diabetes
  • cell death
  • metabolic syndrome
  • adipose tissue
  • insulin resistance