Characterizing the blood stage antimalarial activity of tafenoquine in healthy volunteers experimentally infected with Plasmodium falciparum.
Bridget E BarberAzrin N Abd-RahmanRebecca WebsterAdam J PotterStacey LlewellynLouise MarquartNischal SahaiIndika LeelasenaGeoffrey W BirrellMichael D EdsteinG Dennis ShanksDavid WescheJoerg J MoehrleJames S McCarthyPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
Although a single dose of tafenoquine exhibits potent P. falciparum blood stage antimalarial activity, the estimated doses to effectively clear asexual parasitemia will require prior screening to exclude G6PD deficiency.
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