Value of increased CRP/albumin ratio in predicting embolic events in patients with infective endocarditis.
Saban KelesogluSinan InciMurat GulRamazan OzanIsmail DüzgünAydın TuncayHalil AktaşDeniz ElçikNihat KalayPublished in: Biomarkers in medicine (2023)
Background: The CRP/albumin ratio (CAR), a new inflammatory marker, is associated with adverse outcomes in various cardiovascular diseases. We evaluated the effectiveness of CAR in predicting embolic events in patients diagnosed with infective endocarditis (IE). Methods: A total of 145 patients with IE were included in the study and categorized into two groups according to the presence of embolic events. We retrospectively analyzed the patients' clinical, laboratory and echocardiographic data. Results: CRP (94.2 vs 63.3; p < 0.001) and CAR (25.8 vs 15.1; p < 0.001) values were significantly higher in patients who experienced embolic events. Multivariate analysis showed that a high CAR value (odds ratio: 1.030; 95% CI: 1.000-1.060; p = 0.041) was an independent predictor of embolic events in patients with IE. Conclusion: The CAR is a cheap and easily accessible marker that can predict the development of embolic events in patients diagnosed with IE.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- type diabetes
- systematic review
- prognostic factors
- oxidative stress
- pulmonary hypertension
- metabolic syndrome
- left ventricular
- heart failure
- coronary artery disease
- big data
- patient reported outcomes
- atrial fibrillation