Weak and pleiotropy robust sex-stratified Mendelian randomization in the one sample and two sample settings.

Vasileios KarageorgiouJess TyrrellTrevelyan J MckinleyJack Bowden

Published in: Genetic epidemiology (2023)

We provide a simple but attractive method for weak and pleiotropy robust causal estimation of sexually dimorphic traits on downstream outcomes, by combining several existing approaches in a novel fashion.

Keyphrases

genome wide
type diabetes
adipose tissue
metabolic syndrome
skeletal muscle
weight loss