Excitatory neurons in the lateral parabrachial nucleus mediate the interruptive effect of inflammatory pain on a sustained attention task.

Huan-Yu ZhengYu-Meng ChenYao XuCheng CenYun Wang

Published in: Journal of translational medicine (2023)

Activation of excitatory neurons in the LPBN is a mechanism by which acute inflammatory pain disrupts sustained attention. This finding has implications for the treatment of pain and its cognitive comorbidities.

Keyphrases

chronic pain
pain management
neuropathic pain
spinal cord
working memory
oxidative stress
liver failure
respiratory failure
intensive care unit
postoperative pain