Short-term Outcomes of Pancreatoduodenectomy in Patients with Liver Cirrhosis: A Systematic Review and Meta-analysis.
Shahab HajibandehShahin HajibandehAlwin Puthiyakunnel SajiAyman AshabiChristopher BrownNicholas G MowbrayMatthew MortimerGuy ShinglerAmir KambalBilal Al-SarirehPublished in: Annals of surgery open : perspectives of surgical history, education, and clinical approaches (2024)
Robust evidence with high certainty suggests LC of any severity with or without portal hypertension results in at least a fourfold increase in mortality and a twofold increase in morbidity after pancreatoduodenectomy. Whether such risks increase with the severity of the liver disease or decrease with optimization of underlying liver disease should be the focus of future research.