Association of Interleukin-4 Receptor α Chain I50V Gene Variant (rs1805010) and Asthma in Iranian Population: A Case-control Study.
Masouma MowahediAzam ArameshMozhgan Sorkhi KhouzaniMarjan Sorkhi KhouzaniSaeed DaryanoushMohammad SametMorteza SamadiPublished in: The open respiratory medicine journal (2024)
Asthma patients have a higher prevalence of the I allele, reflecting the significance of Th2 cells. Although total IgE and IL-17A levels increased in both disease subgroups, total IgE level augmentation correlates directly with disease severity, while IL-17A level enhancement does not.
Keyphrases
- chronic obstructive pulmonary disease
- end stage renal disease
- lung function
- induced apoptosis
- ejection fraction
- chronic kidney disease
- risk factors
- allergic rhinitis
- prognostic factors
- peritoneal dialysis
- cell cycle arrest
- copy number
- signaling pathway
- cystic fibrosis
- transcription factor
- oxidative stress
- soft tissue
- patient reported