Effect of valproic acid on miRNAs affecting histone deacetylase in a model of anaplastic thyroid cancer.

Nur Selvi GunelNihal BirdenCansu Caliskan KurtBakiye Goker BagcaBehrouz ShademanFatma SogutluNeslihan Pinar OzatesCigir Biray Avcı

Published in: Molecular biology reports (2021)

VPA can ad-just countless gene expression patterns, including microRNAs (miRNAs), by targeting histone deacetylase (HDAC). However, further studies are required for more accurate results.

Keyphrases

histone deacetylase
gene expression
dna methylation
high resolution
case control
mass spectrometry