Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells.

Banaja P DashTina M SchnöderCarolin KathnerJuliane MohrSönke WeinertCarolin HerzogParimala Sonika GodavarthyCostanza ZanettiFlorian PernerRüdiger Braun-DullaeusBjörn HartlebenTobias B HuberGerd WalzMichael NaumannSarah EllisValera VasioukhinThilo KähneDaniela S KrauseFlorian H Heidel

Published in: Journal of cancer research and clinical oncology (2018)

Our data provide first evidence for an evolutionarily conserved role of the cell fate determinant Scrib in HSC adhesion and migration in vitro and in vivo, a unique function that is not shared with its putative complex partner Llgl1.

Keyphrases

cell fate
stem cells
biofilm formation
bone marrow
transcription factor
electronic health record
big data
cell therapy
escherichia coli
cell adhesion
staphylococcus aureus
data analysis
machine learning
hepatitis c virus
candida albicans
artificial intelligence
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deep learning
hiv testing