Telomere length determined by the fluorescence in situ hybridisation distinguishes malignant and benign cells in cytological specimens.

Yoko MatsudaA SuzukiS EsakaY HamashimaM ImaizumiM KinoshitaH ShirahataY KisoH KojimaM MatsukawaY FujiiN IshikawaJ AidaK TakuboT IshiwataM NishimuraT Arai

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2018)

The present study revealed that telomere length can be used as an indicator to distinguish malignant and benign cells in cytological specimens. This novel approach may help improve diagnosis for cancer patients.

Keyphrases

induced apoptosis
cell cycle arrest
fine needle aspiration
endoplasmic reticulum stress
oxidative stress
cell death
signaling pathway