HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1.

Hang YouGuojing SongZhizhen XuSaipeng ChenWenhao ShenHeting LiuBingqian DengJun LiGang Huang

Published in: Journal of translational medicine (2024)

We confirmed that the HuR/BCAT1 axis plays a crucial role in CRPC progression and suggest that inhibiting the HuR/BCAT1 axis is a promising therapeutic approach for suppressing CRPC progression.

Keyphrases

signaling pathway
binding protein
cell proliferation