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Palladium-Catalyzed Three-Component Coupling Reaction of o-Bromobenzaldehyde, N-Tosylhydrazone, and Methanol.

Lei ZhuXiaojian RenYinghua YuPengcheng OuZhi-Xiang WangXueliang Huang
Published in: Organic letters (2020)
A ligand-controlled palladium-catalyzed three-component reaction of o-bromobenzaldehyde, N-tosylhydrazone, and methanol is described. This reaction uses readily available compounds as starting materials while displaying a broad substrate scope and good functional group compatibility.
Keyphrases
  • electron transfer
  • carbon dioxide
  • room temperature
  • amino acid