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Obesity is associated with IL-6 gene polymorphisms rs1800795 and rs1800796 but not SOCS3 rs4969170.

Gulsah KocTansu DoranMeliha Melin UygurDeniz Kirac
Published in: Molecular biology reports (2022)
In our study, IL-6 rs1800795(G/C) and rs1800796(G/C) polymorphisms appeared to be a risk factor for obesity. The C allele was associated with the obesity phenotypes. However, the SOCS3 rs4969170 (A/G) polymorphism was not linked to an increased risk of obesity. IL-6 polymorphisms may be new targets for obesity treatment.
Keyphrases
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • high fat diet induced
  • type diabetes
  • weight gain
  • body mass index
  • smoking cessation