The Identification of Potential Drugs for Dengue Hemorrhagic Fever: Network-Based Drug Reprofiling Study.
Praveen Kumar Kochuthakidiyel SureshGnanasoundari SekarKavya MalladyWan Suriana Wan Ab RahmanWan Nazatul Shima ShahidanGokulakannan VenkatesanPublished in: JMIR bioinformatics and biotechnology (2023)
Aspirin is not usually prescribed for dengue fever because of bleeding complications, but it has been reported that using aspirin in lower doses is beneficial in the management of diseases with thrombosis. Drug repurposing is an emerging field in which clinical validation and dosage identification are required before the drug is prescribed. Further retrospective and collaborative international trials are essential for understanding the pathogenesis of this condition.
Keyphrases
- zika virus
- low dose
- dengue virus
- aedes aegypti
- cardiovascular events
- drug induced
- antiplatelet therapy
- pulmonary embolism
- atrial fibrillation
- type diabetes
- risk factors
- emergency department
- bioinformatics analysis
- coronary artery disease
- acute coronary syndrome
- percutaneous coronary intervention
- anti inflammatory drugs