Pediatric medulloblastoma express immune checkpoint B7-H3.

S LiG C PoolenL C van VlietJ G SchipperR BroekhuizenM MonnikhofW Van HeckeJ F VermeulenNiels Bovenschen

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2022)

Immune checkpoint B7-H3 is differentially expressed by the large majority of pediatric MB. This further warrants the development of novel B7-H3-directed (immuno)therapeutic methods for children with incurable, metastatic, or chemo-resistant MB.

Keyphrases

squamous cell carcinoma
small cell lung cancer
young adults
photodynamic therapy
cancer therapy
radiation therapy
childhood cancer