Mitochondrial transfer from Adipose stem cells to breast cancer cells drives multi-drug resistance.

Vitale Del VecchioAyesha RehmanSameer Kumar PandaMartina TorsielloMartina MariglianoMaria Maddalena NicolettiGiuseppe Andrea FerraroVincenzo De FalcoRosamaria LappanoEva LietoFrancesca PagliucaCarlo CaputoMarcella La NoceGianpaolo PapaccioVirginia TirinoNirmal RobinsonVincenzo DesiderioFederica Papaccio

Published in: Journal of experimental & clinical cancer research : CR (2024)

We provide a proof-of-concept of the occurrence of Mitochondrial Transfer (MT) from Adipose Stem Cells (ASCs) to BC models. Blocking MT from ASCs to BCCs could be a new effective therapeutic strategy for BC treatment.

Keyphrases

stem cells
breast cancer cells
oxidative stress
adipose tissue
insulin resistance
risk assessment
cell therapy
type diabetes
combination therapy
mesenchymal stem cells
electron transfer
smoking cessation