Effect of Subanesthetic Dose of Esketamine on Perioperative Neurocognitive Disorders in Elderly Undergoing Gastrointestinal Surgery: A Randomized Controlled Trial.

Chao HanHaiyan JiYaxin GuoYuanhui FeiChunhui WangYanbo YuanZhihui RuanTieliang Ma

Published in: Drug design, development and therapy (2023)

Sub-anesthetic doses of esketamine might reduce the incidence of dNCR and improve early postoperative cognitive function in elderly patients undergoing gastrointestinal surgery, which might be related to the anti-neuroinflammation effects of esketamine.

Keyphrases

patients undergoing
minimally invasive
coronary artery bypass
middle aged
surgical site infection
community dwelling
traumatic brain injury
risk factors
cardiac surgery
bipolar disorder
lipopolysaccharide induced
lps induced
inflammatory response
brain injury
atrial fibrillation
subarachnoid hemorrhage