Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin-1, and endothelial dysfunction in streptozotocin treated rats.

Yousif A ShamsaldeenRosemary UgurChristopher D BenhamLisa A Lione

Published in: Diabetes/metabolism research and reviews (2018)

The elevated serum Ox-LDL in hyperglycaemic STZ-diabetic rats may contribute to diabetic endothelial dysfunction, possibly through downregulation of endothelial CAV-1 and eNOS.

Keyphrases

diabetic rats
oxidative stress
endothelial cells
type diabetes
pi k akt
nitric oxide synthase
wound healing
signaling pathway
cell proliferation
low density lipoprotein
insulin resistance