The Clinical Significance and the Potential Regulatory Mechanism of the LncRNA OIP5-AS1 in Paediatric Severe Community-Acquired Pneumonia Blood Through the MiR-150-5p/PDCD4 Axis.

Juan LuQingguo RenWeiwei QiNing YangYuanyuan He

Published in: Immunological investigations (2024)

Increased OIP5-AS1 levels show potential as a valuable diagnostic and prognostic biomarker for paediatric patients with SCAP. This study illustrates its role in regulating cell viability, apoptosis, and the inflammatory response via the miR-150-5p/PDCD4 axis, acting as a ceRNA.

Keyphrases

inflammatory response
community acquired pneumonia
intensive care unit
emergency department
long non coding rna
oxidative stress
endoplasmic reticulum stress
human health
cell death
early onset
lps induced
toll like receptor
risk assessment
signaling pathway