Alpha-Mangostin Improves Cardiac Hypertrophy and Fibrosis and Associated Biochemical Parameters in High-Fat/High-Glucose Diet and Low-Dose Streptozotocin Injection-Induced Type 2 Diabetic Rats.

Vivian SoetiknoAndriyani MurwantaraPrisma AndiniFabrian CharlieGilbert Lazarus Melva LouisaWawaimuli Arozal

Published in: Journal of experimental pharmacology (2020)

These data suggest that administration of alpha-mangostin can effectively attenuate diabetes-induced alteration in cardiac hypertrophy and fibrosis as well as biochemical parameters in HF/HG/STZ rats.

Keyphrases

diabetic rats
oxidative stress
high glucose
low dose
endothelial cells
type diabetes
physical activity
heart failure
high dose
machine learning
glycemic control
atrial fibrillation
drug induced