Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate.

Ileana Ruxandra BotusanXiaowei ZhengSampath NarayananJacob GrünlerVivekananda Gupta SunkariFreja S CalissendorffIshrath AnsurudeenChristopher IlliesJohan SvenssonJohn-Olov JanssonClaes OhlssonKerstin BrismarSergiu-Bogdan Catrina

Published in: PloS one (2018)

Deficiency in the liver-derived IGF-I does not affect wound healing in mice, neither in normoglycemic conditions nor in diabetes.

Keyphrases

wound healing
growth hormone
type diabetes
pi k akt
cardiovascular disease
binding protein
replacement therapy
high fat diet induced
signaling pathway
metabolic syndrome
skeletal muscle