Platelet reactivity and platelet count in women with iron deficiency treated with intravenous iron.
Benjamin K ElstrottHari Hara Sudhan LakshmananAlexander R MelroseKelley R JordanKylee L MartensChih-Jen YangDanielle F PetersonHannah Stowe McMurryCorinne LavasseurJamie O LoSven R OlsonThomas G DeLougheryJoseph E AslanJoseph J ShatzelPublished in: Research and practice in thrombosis and haemostasis (2022)
We find that intravenous iron improves anemia while restoring platelet counts and platelet secretory responses in premenopausal women with iron deficiency. Our results suggest that iron deficiency as well as iron replacement can have a range of effects on platelet production and function. Consequently, platelet reactivity profiles should be further examined in women and other groups with IDA where replacement offers a promising means to improve anemia as well as quality of life.