Using Genomic Variation to Distinguish Ovarian High-Grade Serous Carcinoma from Benign Fallopian Tubes.
Jesus Gonzalez BosquetNicholas D CardilloHenry D ReyesBrian J SmithKimberly K LeslieDavid P BenderMichael J GoodheartEric J DevorPublished in: International journal of molecular sciences (2022)
Genomic variation of HGSC can be used to create prediction models which accurately discriminate cancer from benign tissue. Further refining of these models (early-stage samples, other tumor types) has the potential to lead to detection of ovarian cancer in blood with cell free DNA, even in early stage.