Tumor Mutation Burden and Depression in Lung Cancer: Association With Inflammation.
Daniel C McFarlandDevika R JutagirAndrew H MillerWilliam BreitbartChristian NelsonBarry RosenfeldPublished in: Journal of the National Comprehensive Cancer Network : JNCCN (2021)
These data provide evidence for biologic depression risk in patients with lung cancer who have high levels of TMB. The underlying mechanism of the association is not clearly related to inflammation but warrants further analysis to broadly elucidate the mechanism of biologically derived depression in cancer.