Improved postprocessing of dynamic glucose-enhanced CEST MRI for imaging brain metastases at 3 T.

Yulun WuSophie H A E DerksTobias C WoodErik de BloisAstrid A M van der VeldtMarion SmitsEsther A H Warnert

Published in: European radiology experimental (2023)

• Despite the low signal-to-noise ratio, dynamic glucose-enhanced CEST MRI is feasible at 3 T. • Principal component analyses and dynamic magnetic field correction improve DGE CEST MRI. • DGE CEST MRI does not consequently show changes in brain metastases compared to healthy brain tissue. • Increased DGE CEST MRI in brain metastases, if present, shows overlap with contrast enhancement on T1-weighted images.

Keyphrases

brain metastases
contrast enhanced
small cell lung cancer
magnetic resonance imaging
diffusion weighted imaging
magnetic resonance
computed tomography
high resolution
blood glucose
deep learning
air pollution
type diabetes
mass spectrometry
blood pressure
insulin resistance
resting state
functional connectivity