HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients.

Mohammad Reza MirlashariAnnette VetlesenLise Sofie H Nissen-MeyerChristian NaperGeir Erland TjønnfjordIda Unhammer NjerveFarshid EzliginiBrynjar Fowels LandmarkStephan MeinkePer SandgrenPetter HöglundGeir Hetland

Published in: Transfusion (2021)

The relatively simple acid stripping method can be used with irradiated apheresis PLTs and may prevent transfusion-associated HLA sensitization and overcome PLT refractoriness.

Keyphrases

end stage renal disease
cardiac surgery
chronic kidney disease
peritoneal dialysis
prognostic factors
acute kidney injury
radiation induced
patient reported