Humoral immunity in dually vaccinated SARS-CoV-2-naïve individuals and in booster-vaccinated COVID-19-convalescent subjects.

Vivian GlückLeonid TydykovAnna-Lena MaderAnne-Sophie WardaManuela BertokTanja WeidlichChristine GottwaldJosef KöstlerBernd SalzbergerRalf WagnerMichael KollerAndré GessnerBarbara SchmidtThomas GlückDavid Peterhoff

Published in: Infection (2022)

Long-term humoral immunity differs substantially between dually vaccinated SARS-CoV-2-naïve and COVID-19-convalescent individuals. Booster vaccination after COVID-19 induces a more durable humoral immune response in terms of magnitude and quality as compared to two-dose vaccination in a SARS-CoV-2-naïve background.

Keyphrases

sars cov
immune response
respiratory syndrome coronavirus
dendritic cells
coronavirus disease
toll like receptor