An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer.

Katsuki MiyazakiYuma WadaKeisuke OkunoTatsuro MuranoYuji MorineTetsuya IkemotoYu SaitoHiroaki IkematsuYusuke KinugasaMitsuo ShimadaAjay Goel

Published in: Molecular cancer (2023)

Our novel exosomal miRNA-based liquid biopsy signature robustly identifies T1 CRC patients at risk of LNM in a preoperative setting. This could be clinically transformative in reducing the significant overtreatment burden of this malignancy.

Keyphrases

lymph node metastasis
ultrasound guided
fine needle aspiration
squamous cell carcinoma
papillary thyroid
ionic liquid
genome wide
patients undergoing
risk factors
gene expression