Performance evaluation of lossy quality compression algorithms for RNA-seq data.
Rongshan YuWenxian YangShun WangPublished in: BMC bioinformatics (2020)
Lossy quality value compression can be incorporated into existing RNA-seq analysis pipelines to alleviate the data storage and transmission burdens. However, care should be taken on the selection of compression tools and levels based on the requirements of the downstream analysis pipelines to avoid introducing undesirable adverse effects on the analysis results.