Effect of botulinum toxin on inducibility and maintenance of atrial fibrillation in ovine myocardial tissue.

Alireza NazeriAnand V GanapathyAli MassumiMehran MassumiEgemen TuzunRaymond StainbackAna-Maria SeguraMacarthur A ElaydaMehdi Razavi

Published in: Pacing and clinical electrophysiology : PACE (2017)

The subacute BTX effect reduced the vulnerability of atrial tissue to AF induction and reduced the vagal influence on atrial ERP shortening compared to baseline levels. Direct BTX injection did not cause myocardial dysfunction or histologic adverse effects.

Keyphrases

atrial fibrillation
botulinum toxin
catheter ablation
left atrial
left ventricular
oral anticoagulants
left atrial appendage
direct oral anticoagulants
heart failure
climate change
percutaneous coronary intervention
oxidative stress
ultrasound guided
coronary artery disease