Tyrosine Kinase Inhibitors Improved Survival of Critically Ill EGFR-Mutant Lung Cancer Patients Undergoing Mechanical Ventilation.
I-Hsien LeeChing-Yao YangJin-Yuan ShihChong-Jen YuPublished in: Biomedicines (2021)
For EGFR mutant lung cancer patients suffering from respiratory failure and undergoing mechanical ventilation, TKI may still be useful, especially in those with EGFR del19 mutation or without shock and DM comorbidity.
Keyphrases
- mechanical ventilation
- respiratory failure
- small cell lung cancer
- acute respiratory distress syndrome
- tyrosine kinase
- intensive care unit
- epidermal growth factor receptor
- patients undergoing
- end stage renal disease
- extracorporeal membrane oxygenation
- ejection fraction
- newly diagnosed
- advanced non small cell lung cancer
- type diabetes
- prognostic factors
- adipose tissue
- chronic myeloid leukemia
- skeletal muscle
- insulin resistance
- weight loss
- glycemic control
- free survival