Novel Diclofenac-NO Donor With High Affinity for Human Serum Albumin Induces Endoplasmic Reticulum Stress-mediated Cell Death in Human Pancreatic Cancer Cells.

Koji NishiRyo KandaKaho TakasakiAyano TamoriYoshifumi ArimuraShuhei ImotoHirotaka MuraseKenji TsukigawaMasaki OtagiriKeishi Yamasaki

Published in: Anticancer research (2024)

NDF induces apoptotic cell death by causing endoplasmic reticulum stress. The findings of this study suggest that NDF may become a promising compound for the treatment of pancreatic cancer.

Keyphrases

endoplasmic reticulum stress
cell death
induced apoptosis
human serum albumin
cell cycle arrest
endothelial cells
signaling pathway
cell proliferation
pi k akt