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Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.

Emily A BrownJonathan D LautzTessa R DavisEdward P GniffkeAlison A W VanSchoiackSteven C NeierNoah TashbookChiara NicoliniMargaret FahnestockAdam G SchrumStephen E P Smith
Published in: Molecular autism (2018)
These data highlight the great heterogeneity among models, but suggest that high-dimensional measures of a synaptic protein network may allow differentiation of subtypes of ASD with shared molecular pathology.
Keyphrases
  • single cell
  • mouse model
  • autism spectrum disorder
  • protein protein
  • amino acid
  • binding protein
  • attention deficit hyperactivity disorder
  • big data
  • machine learning
  • artificial intelligence
  • working memory
  • deep learning