Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.
Emily A BrownJonathan D LautzTessa R DavisEdward P GniffkeAlison A W VanSchoiackSteven C NeierNoah TashbookChiara NicoliniMargaret FahnestockAdam G SchrumStephen E P SmithPublished in: Molecular autism (2018)
These data highlight the great heterogeneity among models, but suggest that high-dimensional measures of a synaptic protein network may allow differentiation of subtypes of ASD with shared molecular pathology.