Differentiating primary and secondary FSGS using non-invasive urine biomarkers.

Lorenzo CataneseJustyna SiwyRalph WendtKerstin AmannJoachim BeigeBruce HendryHarald MischakWilliam MullenIan PatersonMario SchifferMichael WolfHarald Rupprecht

Published in: Clinical kidney journal (2023)

A urine peptide-based classifier that selectively detects pFSGS could be developed. Specificity of 95%-99% could be assessed in independent samples. Sensitivity must be confirmed in independent cohorts before routine clinical application.

Keyphrases

clinical practice
contrast enhanced
structural basis