Associations of cardiac stress biomarkers with incident type 2 diabetes and changes in glucose metabolism: KORA F4/FF4 study.
Chaterina SujanaJochen SeisslerJens JordanWolfgang RathmannWolfgang KoenigMichael RodenUlrich MansmannChristian HerderAnnette PetersBarbara ThorandCornelia ThenPublished in: Cardiovascular diabetology (2020)
High plasma concentrations of MR-proANP contributed to a lower risk of incident T2D, whereas high plasma concentrations of copeptin were associated with an increased risk of incident prediabetes/T2D. Furthermore, high plasma concentrations of CT-proET-1 and MR-proADM were associated with increased insulin resistance. Our study provides evidence that biomarkers implicated in cardiac stress are associated with incident T2D and changes in glucose metabolism.