Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway.

Tianhe Huang Fuling ZhouXiaohan YuanTian YangXuan LiangYu WangHonglei TuJiantong ChangKejun Nan Yongchang Wei

Published in: Oxidative medicine and cellular longevity (2019)

ROS-activated ABL1 mediates inflammation through regulating NF-κB1 and STAT3, which subsequently leads to the development of GC and GC-related depression.

Keyphrases

reactive oxygen species
signaling pathway
oxidative stress
depressive symptoms
pi k akt
tyrosine kinase
sleep quality
dna damage
chronic myeloid leukemia
cell death
cell proliferation
induced apoptosis
high resolution
immune response