16S rRNA Gene Sequencing of Gut Microbiota in Rheumatoid Arthritis Treated with 99Tc-MDP.

Zhaowei HuangChangming ChenLinlin TanYi LingWukai MaJin-An Zhang

Published in: Pharmacogenomics and personalized medicine (2024)

This study revealed differences in the composition of the gut microbiota in RA patients before and after 99Tc-MDP treatment. The therapeutic effect of 99Tc MDP is mainly achieved through Bacteroidetes, Prevotella, and Enterococcus. Regulating metabolism and genetic information processing of gut flora may be the mechanism of 99Tc-MDP in treating RA.

Keyphrases

rheumatoid arthritis
end stage renal disease
disease activity
newly diagnosed
genome wide
ejection fraction
chronic kidney disease
ankylosing spondylitis
copy number
prognostic factors
peritoneal dialysis
interstitial lung disease
healthcare
escherichia coli
idiopathic pulmonary fibrosis
replacement therapy